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KMID : 0383820090660010027
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Tuberculosis and Respiratory Diseases
2009 Volume.66 No. 1 p.27 ~ p.32
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Clinical Characteristics and Prognosis of Lung Cancer Patients
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Moon Kyoung-Min
Lee Yang-Deok
Cho Yong-Seon
Han Min-Soo
Lee Seong-Kyu
Na Dong-Jip
Jeon Ho-Seok
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Abstract
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Background: The management of patients with lung cancer has improved recently, and many of them will require admission to the medical intensive care unit (MICU). The aim of this study was to examine the clinical characteristics
and to identify risk factors for mortality in patients with lung cancer admitted to the MICU.
Methods: We conducted retrospective analysis on 88 patients with lung cancer admitted to the MICU between April 2004 and March 2008.
Results: Of the 88 patients (mean age, 66 years), 71 patients (80.7%) had non-small cell lung cancer and 17
patients (19.3%) had small cell lung cancer. Distant metastasis were present in 79 patients (89.8%). The main reasons for MICU admission were acute respiratory failure (77.3%), sepsis (11.4%), and central nervous system dysfunction (4.5%). Mechanical ventilation was used in 54 patients (61.4%). Acute Physiology and Chronic Health Evaluation (APACHE) II score, length of MICU stay, need for mechanical ventilation, source of MICU admission were correlated with MICU
mortality. The type of lung cancer and metastasis were not predictive factors of death in MICU.
Conclusion: Most common reason for ICU admission was acute respiratory failure. Mortality rate of lung cancer patients admitted to the MICU was 65.9%. APACHE II score, length of ICU stay, need for mechanical ventilation, source of MICU admission were predicted factors of death in the MICU.
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KEYWORD
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Lung cancer, Intensive care unit, APACHE II score, Mechanical ventilation
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